Behavioral and psychosocial responses to genomic testing for colorectal cancer risk
نویسندگان
چکیده
منابع مشابه
Interest and informational preferences regarding genomic testing for modest increases in colorectal cancer risk.
BACKGROUND/AIMS This study explored the interest in genomic testing for modest changes in colorectal cancer risk and preferences for receiving genomic risk communications among individuals with intermediate disease risk due to a family history of colorectal cancer. METHODS Surveys were conducted on 272 men and women at intermediate risk for colorectal cancer enrolled in a randomized trial com...
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abstract: colorectal cancer (crc) is the third most common cancer in men and the second most common cancer in women worldwide. both genetic and epigenetic alterations are common in crc and are the driving force of tumorigenesis. chromosomal instability, microsatellite instability and cpg island methylator phenotype pathways are responsible for genetic instability in colorectal cancer. chromosom...
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BACKGROUND Individuals who are not adherent to colorectal cancer screening have a greater prevalence of several other behavioral risk factors for colorectal cancer than adherent individuals. However, previous relevant studies have typically not considered the co-occurrence of such behavioral risk factors at the individual level. In the current study, we examined the prevalence, patterns, and pr...
متن کاملGenomic testing in colorectal cancer: how much is enough?
Colorectal cancer has been extensively molecularly characterized in recent years. In addition to furthering the understanding of biologic hallmarks of the disease, the ultimate goal of these studies has been to provide tools that would allow us to identify subgroups of colorectal cancer with prognostic and predictive implications, either for the anticipation of toxicity or for selection of the ...
متن کاملWho gets genomic testing for breast cancer recurrence risk?
BACKGROUND/AIMS Our study examined whether patient characteristics, beliefs and decision-making styles were associated with uptake of genomic testing for breast cancer recurrence risk. METHODS Participants were 132 early-stage breast cancer patients eligible for the Oncotype DX genomic test. We interviewed patients in 2009-2010 and obtained information from medical charts. RESULTS Half of t...
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ژورنال
عنوان ژورنال: Genomics
سال: 2013
ISSN: 0888-7543
DOI: 10.1016/j.ygeno.2013.04.002